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An Alu Transposition Model for the Origin and Expansion of Human Segmental Duplications

Relative to genomes of other sequenced organisms, the human genome appears particularly enriched for large, highly homologous segmental duplications (⩾90% sequence identity and ⩾10 kbp in length). The molecular basis for this enrichment is unknown. We sought to gain insight into the mechanism of ori...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bailey, Jeffrey A., Liu, Ge, Eichler, Evan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180605/
https://ncbi.nlm.nih.gov/pubmed/14505274
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