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Carbamate Transport in Carbamoyl Phosphate Synthetase: A Theoretical and Experimental Investigation
The transport of carbamate through the large subunit of carbamoyl phosphate synthetase (CPS) from Escherichia coli was investigated by molecular dynamics and site-directed mutagenesis. Carbamate, the product of the reaction involving ATP, bicarbonate and ammonia, must be delivered from the site of f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847351/ https://ncbi.nlm.nih.gov/pubmed/20187643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910441v |
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