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The human Holliday junction resolvase GEN1 rescues the meiotic phenotype of a Schizosaccharomyces pombe mus81 mutant

A key step in meiotic recombination involves the nucleolytic resolution of Holliday junctions to generate crossovers. Although the enzyme that performs this function in human cells is presently unknown, recent studies led to the identification of the XPG-family endonuclease GEN1 that promotes Hollid...

詳細記述

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書誌詳細
主要な著者: Lorenz, Alexander, West, Stephen C., Whitby, Matthew C.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847240/
https://ncbi.nlm.nih.gov/pubmed/20040574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1179
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