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Silencing by imprinted noncoding RNAs: is transcription the answer?

Non-coding RNAs (ncRNAs) with gene regulatory functions are starting to be seen as a common feature of mammalian gene regulation with the discovery that most of the transcriptome is ncRNA. The prototype has long been the Xist ncRNA, which induces X-chromosome inactivation in female cells. However, a...

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Autori principali: Pauler, Florian M., Koerner, Martha V., Barlow, Denise P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847181/
https://ncbi.nlm.nih.gov/pubmed/17445943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2007.03.018
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