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Helminth infection impairs the immunogenicity of a Plasmodium falciparum DNA vaccine, but not irradiated sporozoites, in mice

Development of an effective vaccine against malaria remains a priority. However, a significant number of individuals living in tropical areas are also likely to be co-infected with helminths, which are known to adversely affect immune responses to a number of different existing vaccines. Here we com...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Noland, Gregory S., Chowdhury, Debabani Roy, Urban, Joseph F., Zavala, Fidel, Kumar, Nirbhay
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846978/
https://ncbi.nlm.nih.gov/pubmed/20188676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.02.055
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