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In vitro activities of metronidazole and its hydroxy metabolite against Bacteroides spp.

Metronidazole is metabolized to two major oxidative products: an acid metabolite and a hydroxy metabolite. While the activity of the acid metabolite is negligible, the activity of the hydroxy metabolite is approximately 65% of the activity of the parent drug. Pharmacokinetic studies of metronidazole...

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Dettagli Bibliografici
Autori principali: Pendland, S L, Piscitelli, S C, Schreckenberger, P C, Danziger, L H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC284692/
https://ncbi.nlm.nih.gov/pubmed/7811027
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