Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance

BACKGROUND: Pulmonary fibrosis is a progressive and lethal disorder. Although the precise mechanisms of pulmonary fibrosis are not fully understood, oxidant/antioxidant and Th1/Th2 balances may play an important role in many of the processes of inflammation and fibrosis. The transcription factor Nrf...

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Hlavní autoři: Kikuchi, Norihiro, Ishii, Yukio, Morishima, Yuko, Yageta, Yuichi, Haraguchi, Norihiro, Itoh, Ken, Yamamoto, Masayuki, Hizawa, Nobuyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846897/
https://ncbi.nlm.nih.gov/pubmed/20298567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-31
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