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Need-Based Up-Regulation of Protein Levels in Response to Deletion of Their Duplicate Genes
Many duplicate genes maintain functional overlap despite divergence over long evolutionary time scales. Deleting one member of a paralogous pair often has no phenotypic effect, unless its paralog is also deleted. It has been suggested that this functional compensation might be mediated by active up-...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846854/ https://ncbi.nlm.nih.gov/pubmed/20361019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000347 |
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