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Increase in gene-transcript levels as indicators of up-regulation of the unfolded protein response in spontaneous canine tumors

The unfolded protein response (UPR), a conserved cellular response to stressors such as hypoxia and nutrient deprivation, is associated with angiogenesis and metastasis in tumor cells. This article discusses a pilot study conducted to determine whether components of the UPR could be identified in sp...

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Detalhes bibliográficos
Main Authors: Elliot, Kirsten, MacDonald-Dickinson, Valerie, Linn, Kathleen, Simko, Elemir, Misra, Vikram
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Veterinary Medical Association 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068406/
https://ncbi.nlm.nih.gov/pubmed/24982546
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