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Identification of an ancient Bmp4 mesoderm enhancer located 46 kilobases from the promoter

Bone morphogenetic protein 4 (Bmp4) is a multi-functional, developmentally regulated gene that is essential for mouse development, as most Bmp4-null mouse embyros die at the onset of gastrulation and fail to develop mesoderm. Little is known about the transcriptional regulation of Bmp4. To identify...

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Main Authors: Chandler, Kelly J., Chandler, Ronald L., Mortlock, Douglas P.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846791/
https://ncbi.nlm.nih.gov/pubmed/19159624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.12.033
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