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MAPK substrate competition integrates patterning signals in the Drosophila embryo

Terminal regions of the Drosophila embryo are patterned by the localized activation of the Mitogen Activated Protein Kinase (MAPK) pathway [1]. This depends on the MAPK-mediated downregulation of Capicua (Cic), a repressor of the terminal gap genes [2, 3]. We established that downregulation of Cic i...

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Autores principales: Kim, Yoosik, Coppey, Mathieu, Grossman, Rona, Ajuria, Leiore, Jiménez, Gerardo, Paroush, Ze’ev, Shvartsman, Stanislav Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846708/
https://ncbi.nlm.nih.gov/pubmed/20171100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.01.019
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