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Phosphorylation of the Drosophila melanogaster RNA–Binding Protein HOW by MAPK/ERK Enhances Its Dimerization and Activity

Drosophila melanogaster Held Out Wings (HOW) is a conserved RNA–binding protein (RBP) belonging to the STAR family, whose closest mammalian ortholog Quaking (QKI) has been implicated in embryonic development and nervous system myelination. The HOW RBP modulates a variety of developmental processes b...

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Detalhes bibliográficos
Main Authors: Nir, Ronit, Grossman, Rona, Paroush, Ze'ev, Volk, Talila
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315481/
https://ncbi.nlm.nih.gov/pubmed/22479211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002632
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