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Controllable Self-Assembly of Nanoparticles for Specific Delivery of Multiple Therapeutic Molecules to Cancer Cells Using RNA Nanotechnology

By utilizing RNA nanotechnology, we engineered both therapeutic siRNA and a receptor-binding RNA aptamer into individual pRNAs of phi29's motor. The RNA building block harboring siRNA or other therapeutic molecules was fabricated subsequently into a trimer through the interaction of engineered...

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Detaylı Bibliyografya
Asıl Yazarlar: Khaled, Annette, Guo, Songchuan, Li, Feng, Guo, Peixuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846701/
https://ncbi.nlm.nih.gov/pubmed/16159227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl051264s
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