Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide.

The abilities of 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide, 22,23-epoxy-2-aza-2,3-dihydrosqualene-N-oxide, to inhibit sterol biosynthesis were studied in microsomes and cells of Saccharomyces cerevisiae and Candida albicans. 22,23-Epoxy-2-aza-2,3-dihydrosqualene, which diff...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Balliano, G, Milla, P, Ceruti, M, Carrano, L, Viola, F, Brusa, P, Cattel, L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7810997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.1904
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