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Validation of [22,23-3H]cholic acid as a stable tracer through conversion to deoxycholic acid in human subjects

Bile acids labeled with 3H on the sterol nucleus lose a substantial fraction of label during enterohepatic cycling and conversion to secondary bile acids. We tested the isotopic stability of a side-chain 3H label, [22,23-3H]cholic acid in humans. The 3H-labeled compound was administered simultaneous...

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Bibliografiske detaljer
Principais autores: W C Duane, C D Schteingart, H T Ton-Nu, A F Hofmann
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 1996-02-01
Serier:Journal of Lipid Research
Online adgang:http://www.sciencedirect.com/science/article/pii/S002222752037629X
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