Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets.

Single-dose treatments (5 to 40 mg/kg of body weight given intraperitoneally) of ferrets with 2'-deoxy-2'-fluoroguanosine or its prodrug, 2,6-diamino-purine-2'-fluororiboside, 1 h after infection with influenza A virus significantly inhibited replication of virus in the upper respiratory tract, resu...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Jakeman, K J, Tisdale, M, Russell, S, Leone, A, Sweet, C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284652/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7986023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.8.1864
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