The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study

The surge in dopamine in ventral striatal regions in response to drugs of abuse and drug-associated stimuli is a final common pathway of addiction processes. GABA B agonists exert their effects indirectly, by quieting dopaminergic afferents. The ability of the GABA B agonist, baclofen to ameliorate...

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Hlavní autoři: Franklin, Teresa R., Harper, Derek, Kampman, Kyle, Kildea, Susan, Jens, Will, Lynch, Kevin, O’Brien, Charles P., Childress, Anna Rose
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846510/
https://ncbi.nlm.nih.gov/pubmed/19398283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2009.02.014
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