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UDP-GlcNAc: Glycoprotein N-Acetylglucosamine-1-Phosphotransferase Mediates the Initial Step in the Formation of the Methylphosphomannosyl Residues on the High Mannose Oligosaccharides of Dictyostelium Discoideum Glycoproteins

The Dictyostelium discoideum gene gpt1 encodes a protein XP_638036 with sequence similarity to the α/β subunits of mammalian UDP-GlcNAc:Glycoprotein N-acetylglucosamine-1-phosphotransferase. We now demonstrate that extracts of D. discoideum clones with mutations in this gene transfer GlcNAc-P from U...

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Detalhes bibliográficos
Main Authors: Qian, Yi, West, Christopher M., Kornfeld, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846398/
https://ncbi.nlm.nih.gov/pubmed/20170636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.02.055
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