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Potent induction of B- and T-cell immunity against human carcinoembryonic antigen-expressing tumors in human carcinoembryonic antigen transgenic mice mediated by direct lentivector injection

The applicability of immunotherapy would be dramatically broadened to a greater number of recipients if direct “off-the-shelf” products could be engineered to engender functionally potent immune responses against true “self”-tumor antigens. This would obviate the need for ex vivo culture of dendriti...

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Main Authors: Loisel-Meyer, Severine, Felizardo, Tania, Mariotti, Jacopo, Mossoba, Miriam E., Foley, Jason E., Kammerer, Robert, Mizue, Nobuo, Keefe, Robert, McCart, J. Andrea, Zimmermann, Wolfgang, Dropulic, Boro, Fowler, Daniel H., Medin, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846382/
https://ncbi.nlm.nih.gov/pubmed/19276164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0769
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