In vitro anti-Mycobacterium avium activities of quinolones: predicted active structures and mechanistic considerations.

The relationship between the structures of quinolones and their anti-Mycobacterium avium activities has been previously derived by using the Multiple Computer-Automated Structure Evaluation program. A number of substructural constraints required to overcome the resistance of most of the strains have...

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Dettagli Bibliografici
Autori principali: Klopman, G, Li, J Y, Wang, S, Pearson, A J, Chang, K, Jacobs, M R, Bajaksouzian, S, Ellner, J J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC284638/
https://ncbi.nlm.nih.gov/pubmed/7986010
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