In vitro anti-Mycobacterium avium activities of quinolones: predicted active structures and mechanistic considerations.

The relationship between the structures of quinolones and their anti-Mycobacterium avium activities has been previously derived by using the Multiple Computer-Automated Structure Evaluation program. A number of substructural constraints required to overcome the resistance of most of the strains have...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Klopman, G, Li, J Y, Wang, S, Pearson, A J, Chang, K, Jacobs, M R, Bajaksouzian, S, Ellner, J J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7986010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.8.1794
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