Inhibition of human immunodeficiency virus type 1 replication by SDZ NIM 811, a nonimmunosuppressive cyclosporine analog.

(Me-Ile-4)cyclosporin (SDZ NIM 811) is a 4-substituted cyclosporin which is devoid of immunosuppressive activity but retains full capacity for binding to cyclophilin and exhibits potent anti-human immunodeficiency virus type 1 (HIV-1) activity. SDZ NIM 811 selectively inhibits HIV-1 replication in T...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Rosenwirth, B, Billich, A, Datema, R, Donatsch, P, Hammerschmid, F, Harrison, R, Hiestand, P, Jaksche, H, Mayer, P, Peichl, P
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7527198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.8.1763
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