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Inhibition of human immunodeficiency virus type 1 replication by SDZ NIM 811, a nonimmunosuppressive cyclosporine analog.

(Me-Ile-4)cyclosporin (SDZ NIM 811) is a 4-substituted cyclosporin which is devoid of immunosuppressive activity but retains full capacity for binding to cyclophilin and exhibits potent anti-human immunodeficiency virus type 1 (HIV-1) activity. SDZ NIM 811 selectively inhibits HIV-1 replication in T...

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Bibliographic Details
Main Authors: Rosenwirth, B, Billich, A, Datema, R, Donatsch, P, Hammerschmid, F, Harrison, R, Hiestand, P, Jaksche, H, Mayer, P, Peichl, P
Format: Artigo
Language:Inglês
Published: 1994
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC284634/
https://ncbi.nlm.nih.gov/pubmed/7527198
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