Quantitative relationships between zidovudine exposure and efficacy and toxicity.

We examined the relationship between the concentrations of zidovudine in plasma given by continuous intravenous infusion to human immunodeficiency virus-positive pediatric patients and a surrogate marker of outcome (measured by the increase in the number of CD4-positive T cells) as well as drug-medi...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Drusano, G L, Balis, F M, Gitterman, S R, Pizzo, P A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7986002/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.8.1726
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