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Quantitative relationships between zidovudine exposure and efficacy and toxicity.

We examined the relationship between the concentrations of zidovudine in plasma given by continuous intravenous infusion to human immunodeficiency virus-positive pediatric patients and a surrogate marker of outcome (measured by the increase in the number of CD4-positive T cells) as well as drug-medi...

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Détails bibliographiques
Auteurs principaux: Drusano, G L, Balis, F M, Gitterman, S R, Pizzo, P A
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC284629/
https://ncbi.nlm.nih.gov/pubmed/7986002
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