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Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis

Evaluation of transcriptional changes in the striatum may be an effective approach to understanding the natural history of changes in expression contributing to the pathogenesis of Huntington disease (HD). We have performed genome-wide expression profiling of the YAC128 transgenic mouse model of HD...

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Detalhes bibliográficos
Main Authors: Becanovic, Kristina, Pouladi, Mahmoud A., Lim, Raymond S., Kuhn, Alexandre, Pavlidis, Paul, Luthi-Carter, Ruth, Hayden, Michael R., Leavitt, Blair R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846159/
https://ncbi.nlm.nih.gov/pubmed/20089533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq018
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