IFN-γ Regulates the Requirement for IL-17 in Proteoglycan-Induced Arthritis

The contribution of the pro-inflammatory cytokines IFN-γ and IL-17 to the pathogenesis of experimental arthritis is controversial. In proteoglycan-induced arthritis (PGIA) severe arthritis is dependent on the production of IFN-γ whereas IL-17 is dispensable. In collagen-induced arthritis (CIA) and a...

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Autori principali: Doodes, Paul D., Cao, Yanxia, Hamel, Keith M., Wang, Yumei, Rodeghero, Rachel L., Mikecz, Katalin, Glant, Tibor T., Iwakura, Yoichiro, Finnegan, Alison
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846113/
https://ncbi.nlm.nih.gov/pubmed/20028652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902907
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