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Macrolide antibiotics protect against endotoxin-induced vascular leakage and neutrophil accumulation in rat trachea.
We studied the effects of macrolides on lipopolysaccharide (LPS)-induced airway inflammation in the rat tracheal mucosa. Erythromycin and roxithromycin dose dependently inhibited microvascular leakage and neutrophil recruitment induced by LPS. This inhibitory action on vascular permeability was abol...
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| Gepubliceerd in: | Antimicrob Agents Chemother |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
1994
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7979298/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.7.1641 |
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