Differential antiviral activities and intracellular metabolism of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine in human cells.

Dideoxynucleosides such as 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxyinosine (ddI) can effectively inhibit the replication of human immunodeficiency virus (HIV) in T lymphoid cells. There is evidence that HIV can infect and replicate in other cells including monocytoid cells and macrophages....

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Mukherji, E, Au, J L, Mathes, L E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284595/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7526781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.7.1573
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