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Dominant-Negative Regulation of Cell Surface Expression by a Pentapeptide Motif at the Extreme COOH Terminus of an Slo1 Calcium-Activated Potassium Channel Splice Variant

Large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels regulate the physiology of many cell types. A single vertebrate gene variously known as Slo1, KCa1.1, or KCNMA1 encodes the pore-forming subunits of BK(Ca) channel but is expressed in a potentially very large number of alternative splice vari...

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Bibliographic Details
Main Authors: Chiu, Yu-Hsin, Alvarez-Baron, Claudia, Kim, Eun Young, Dryer, Stuart E.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845944/
https://ncbi.nlm.nih.gov/pubmed/20051533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.061929
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