The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice

The vascular pathobiology of sickle cell anemia involves inflammation, coagulation, vascular stasis, reperfusion injury, iron-based oxidative biochemistry, deficient nitric oxide (NO) bioavailability, and red cell sickling. These disparate pathobiologies intersect and overlap, so it is probable that...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hebbel, Robert P., Vercellotti, Gregory M., Pace, Betty S., Solovey, Anna N., Kollander, Rahn, Abanonu, Chine F., Nguyen, Julia, Vineyard, Julie V., Belcher, John D., Abdulla, Fuad, Osifuye, Shadé, Eaton, John W., Kelm, Robert J., Slungaard, Arne
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2010
विषय:
Red Cells, Iron, and Erythropoiesis
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845902/
https://ncbi.nlm.nih.gov/pubmed/20053759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-204990
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