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Chemotherapy rescues tumor-driven aberrant CD4(+) T-cell differentiation and restores an activated polyfunctional helper phenotype
The functional development of tumor-specific CD4(+) T cells has a critical impact on the outcome of antitumor immune responses. Adoptive immunotherapy involving tumor-specific CD4(+) T cells has shown encouraging clinical benefits in some cancer patients. To mount an effective antitumor immunity, it...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845898/ https://ncbi.nlm.nih.gov/pubmed/20118405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-253336 |
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