IL-7 signaling imparts polyfunctionality and stemness potential to CD4(+) T cells

The functional status of CD4(+) T cells is a critical determinant of antitumor immunity. Polyfunctional CD4(+) T cells possess the ability to concomitantly produce multiple Th1-type cytokines, exhibiting a functional attribute desirable for cancer immunotherapy. However, the mechanisms by which thes...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Ding, Zhi-Chun, Liu, Chufeng, Cao, Yang, Habtetsion, Tsadik, Kuczma, Michal, Pi, Wenhu, Kong, Heng, Cacan, Ercan, Greer, Susanna F., Cui, Yan, Blazar, Bruce R., Munn, David H., Zhou, Gang
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938319/
https://ncbi.nlm.nih.gov/pubmed/27471650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1171445
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