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Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?

Tyrosine kinases are important cellular signaling proteins that have a variety of biological activities including cell proliferation and migration. Multiple kinases are involved in angiogenesis, including receptor tyrosine kinases such as the vascular endothelial growth factor receptor. Inhibition o...

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Bibliografiske detaljer
Main Authors: Gotink, Kristy J., Verheul, Henk M. W.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845892/
https://ncbi.nlm.nih.gov/pubmed/20012482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-009-9160-6
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