Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase.

The lipopeptide antifungal agents, echinocandins, papulacandins, and pneumocandins, kill Candida albicans by inhibiting glucan synthesis. For this fungus, there is a good correlation of in vitro enzyme inhibition with in vitro assays of MICs. Semisynthetic lipopeptides such as cilofungin, LY303366,...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Kurtz, M B, Heath, I B, Marrinan, J, Dreikorn, S, Onishi, J, Douglas, C
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284580/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7979276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.7.1480
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