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Molecular Mechanisms of T cell Receptor and Costimulatory Molecule Ligation/Blockade in Autoimmune Disease Therapy
Pro-inflammatory CD4(+) T cell mediated autoimmune diseases, such as multiple sclerosis and type 1 diabetes, are hypothesized to be initiated and maintained by activated antigen presenting cells (APCs) presenting self-antigen to self-reactive interferon-gamma (IFN-γ) and interleukin-17 (IL-17) produ...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845642/ https://ncbi.nlm.nih.gov/pubmed/19426232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2009.00773.x |
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