Genome-Wide Association Study Identifies GPC5 as a Novel Genetic Locus Protective against Sudden Cardiac Arrest

BACKGROUND: Existing studies indicate a significant genetic component for sudden cardiac arrest (SCA) and genome-wide association studies (GWAS) provide an unbiased approach for identification of novel genes. We performed a GWAS to identify genetic determinants of SCA. METHODOLOGY/PRINCIPAL FINDINGS...

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Detalhes bibliográficos
Main Authors: Arking, Dan E., Reinier, Kyndaron, Post, Wendy, Jui, Jonathan, Hilton, Gina, O'Connor, Ashley, Prineas, Ronald J., Boerwinkle, Eric, Psaty, Bruce M., Tomaselli, Gordon F., Rea, Thomas, Sotoodehnia, Nona, Siscovick, David S., Burke, Gregory L., Marban, Eduardo, Spooner, Peter M., Chakravarti, Aravinda, Chugh, Sumeet S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845611/
https://ncbi.nlm.nih.gov/pubmed/20360844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009879
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