Genetic Variations in NOS1AP are Associated with Sudden Cardiac Death in U.S. White Community Based Populations

BACKGROUND: The electrocardiographic QT interval is associated with risk of sudden cardiac death (SCD). A previous genome-wide association study demonstrated that allelic variants (rs10494366 and rs4657139) in NOS1AP, which encodes a carboxy-terminal PDZ ligand of neuronal nitric oxide synthase, are...

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Auteurs principaux: Kao, WH Linda, Arking, Dan E, Post, Wendy, Rea, Thomas D, Sotoodehnia, Nona, Prineas, Ronald J, Bishe, Bryan, Doan, Betty Q, Boerwinkle, Eric, Psaty, Bruce M, Tomaselli, Gordon, Coresh, Josef, Siscovick, David S, Marban, Eduardo, Spooner, Peter M, Burke, Greg L, Chakravarti, Aravinda
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782762/
https://ncbi.nlm.nih.gov/pubmed/19204306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.791723
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