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Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin
Immune responses to autoantigens are in part controlled by deletion of autoreactive cells through genetically regulated selection mechanisms. We have directly analyzed peripheral CD4+ proinsulin (PI) 76–90 (SLQPLALEGSLQKRG)-specific T cells using soluble fluorescent major histocompatibility complex...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845516/ https://ncbi.nlm.nih.gov/pubmed/20054344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.108 |
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