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Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin

Immune responses to autoantigens are in part controlled by deletion of autoreactive cells through genetically regulated selection mechanisms. We have directly analyzed peripheral CD4+ proinsulin (PI) 76–90 (SLQPLALEGSLQKRG)-specific T cells using soluble fluorescent major histocompatibility complex...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Durinovic-Belló, I, Wu, R P, Gersuk, V H, Sanda, S, Shilling, H G, Nepom, G T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845516/
https://ncbi.nlm.nih.gov/pubmed/20054344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.108
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