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INTRACELLULAR NAD LEVELS REGULATE TNF-α PROTEIN SYNTHESIS IN A SIRTUIN-DEPENDENT MANNER
Uncontrolled TNF-α synthesis is known to play an important role in numerous inflammatory disorders, and multiple transcriptional and post-transcriptional regulatory mechanisms have therefore evolved to dampen the production of this important pro-inflammatory cytokine. By examining the anti-inflammat...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845476/ https://ncbi.nlm.nih.gov/pubmed/19151729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1906 |
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