INTRACELLULAR NAD LEVELS REGULATE TNF-α PROTEIN SYNTHESIS IN A SIRTUIN-DEPENDENT MANNER

Uncontrolled TNF-α synthesis is known to play an important role in numerous inflammatory disorders, and multiple transcriptional and post-transcriptional regulatory mechanisms have therefore evolved to dampen the production of this important pro-inflammatory cytokine. By examining the anti-inflammat...

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Detalhes bibliográficos
Main Authors: Van Gool, Frédéric, Galli, Mara, Gueydan, Cyril, Kruys, Véronique, Bedalov, Antonio, Mostoslavsky, Raul, Alt, Frederick W., De Smedt, Thibaut, Leo, Oberdan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845476/
https://ncbi.nlm.nih.gov/pubmed/19151729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1906
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