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Transplacental pharmacokinetics of dideoxyinosine in pigtailed macaques.

To determine whether dideoxyinosine is actively transported across the placenta, four pregnant macques (Macaca nemestrina) near term and their fetuses were infused intravenously in random order with simultaneous doses of dideoxyinosine (42.5 micrograms/min/kg of body weight) and antipyrine (41.7 mic...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Pereira, C M, Nosbisch, C, Winter, H R, Baughman, W L, Unadkat, J D
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8031046/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.781
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