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Transplacental pharmacokinetics of dideoxyinosine in pigtailed macaques.

To determine whether dideoxyinosine is actively transported across the placenta, four pregnant macques (Macaca nemestrina) near term and their fetuses were infused intravenously in random order with simultaneous doses of dideoxyinosine (42.5 micrograms/min/kg of body weight) and antipyrine (41.7 mic...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pereira, C M, Nosbisch, C, Winter, H R, Baughman, W L, Unadkat, J D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8031046/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.781
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