Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations.

The emergence of multidrug-resistant strains of Mycobacterium tuberculosis has resulted in increased interest in the fluoroquinolones (FQs) as antituberculosis agents. To investigate the frequency and mechanisms of FQ resistance in M. tuberculosis, we cloned and sequenced the wild-type gyrA and gyrB...

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Yayımlandı:	Antimicrob Agents Chemother
Asıl Yazarlar:	Takiff, H E, Salazar, L, Guerrero, C, Philipp, W, Huang, W M, Kreiswirth, B, Cole, S T, Jacobs, W R, Telenti, A
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1994
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8031045/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.773
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