Pharmacokinetics and safety of a unilamellar liposomal formulation of amphotericin B (AmBisome) in rabbits.

A unilamellar liposomal formulation of amphotericin B (LAmB) known as AmBisome was safely administered intravenously to 20 rabbits at 0.5, 1.0, 2.5, 5, or 10 mg/kg of body weight, whereas of 12 rabbits given desoxycholate amphotericin B (DAmB) intravenously at 0.5, 1.0, or 1.5 mg/kg, 2 died of acute...

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發表在:	Antimicrob Agents Chemother
Principais autores:	Lee, J W, Amantea, M A, Francis, P A, Navarro, E E, Bacher, J, Pizzo, P A, Walsh, T J
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1994
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8031034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.713
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