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Mouse Models of p53 Functions
Studies in mice have yielded invaluable insight into our understanding of the p53 pathway. Mouse models with activated p53, no p53, and mutant p53 have queried the role of p53 in development and tumorigenesis. In these models, p53 is activated and stabilized via redundant posttranslational modificat...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2010
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845198/ https://ncbi.nlm.nih.gov/pubmed/20452944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001115 |
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