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Improvement of the design and generation of highly specific plant knockdown lines using primary synthetic microRNAs (pri-smiRNAs)

BACKGROUND: microRNAs (miRNAs) are endogenous small non-coding RNAs that post-transcriptionally regulate gene expression. In plants, they typically show high complementarity to a single sequence motif within their target mRNAs and act by catalyzing specific mRNA cleavage and degradation. miRNAs are...

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Autori principali: Niemeier, Sandra, Alves, Leonardo, Merkle, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845148/
https://ncbi.nlm.nih.gov/pubmed/20202197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-59
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