Fever and associated changes in glomerular filtration rate erase anticipated diurnal variations in aminoglycoside pharmacokinetics.

Netilmicin (4.5 mg/kg of lean body weight) was administered intravenously once every 24 h at 10 a.m. to 23 patients (group I) and at 10 p.m. to 20 patients (group II) with severe infection. No significant differences (P > 0.05) in peak and trough concentrations in serum were found between groups...

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Библиографические подробности
Главные авторы: Fauvelle, F, Perrin, P, Belfayol, L, Boukari, M, Cherrier, P, Bosio, A M, Tod, M, Coulaud, J M, Petitjean, O
Формат: Artigo
Язык:Inglês
Опубликовано: 1994
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC284509/
https://ncbi.nlm.nih.gov/pubmed/8203864
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