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Fast and SNP-tolerant detection of complex variants and splicing in short reads

Motivation: Next-generation sequencing captures sequence differences in reads relative to a reference genome or transcriptome, including splicing events and complex variants involving multiple mismatches and long indels. We present computational methods for fast detection of complex variants and spl...

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Autors principals: Wu, Thomas D., Nacu, Serban
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844994/
https://ncbi.nlm.nih.gov/pubmed/20147302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq057
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